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Resveratrol
Source:plantextract space Writer:lugos Public date:2007-01-05    
 

   
   
   
 
   
   
   
 PRODUCT NAME:    Resveratrol
 ACTIVE CONSTITUENTS:   Resveratrol
 SPECIFICATION:   98%
 TEST METHOD:   HPLC
 ORIGIN:   Made in china
 ASK PRICE:   info@plantextra.com

 

                                                                                                                                                                                                    

PHARMACOLOGICAL ACTIVITIES:

           Resveratrol in Polygonum is the major active ingredient, which has effect to anti-cancer and to strengthen

immunity through research.

 
Resveratrol has very strong effect to clear oxidant free radical, along with inhibiting the damage and mutation

tothe body caused by free radical. The research to cytology based on in vitro cancer cell proved that

Resveratrol could inhibit the breeding of various cancer cells.  The proliferation of cancer cells is due to

secretion of ROS by stimulus and a certain quantity of O-2 and H2O2.  Another research proved that

Resveratrol has very stronginhibition to the total ROS self-secreted by cancer cells.  It inhibits the density

of O-2 , stops the changes of cancer cells from S to G2, thus strongly inhibiting the breeding of cancer cells.


The characteristic of Resveratrol to anti-cancer means it has inhibition even deterioration to the three main

stages of the cancer at the start, breeding and development.  The scientists in National University of

Singaporehave found by study that Resveratrol can induce the splitting of DNA of leukocyte for HL60 in

human body, and further lead membrane phospholipid to lose non-symmetry.  This shows it may induce the

death in sequence of leukocyte for HL60.  Another discovery is also found to show that the death of cancer

cells relying on the interaction between CD95 and CD95L.  Resveratrol can increase the value of HL60

cells and CD95L in T47Dbreast cancer cell. The scientists treat the breast cancer cell by using Resveratrol,

the result shows CD95 andCD95L system reaching a new balance, which leading 63% of T47D breast

cancer cell dying 18 hours later

.
Deal with the normal ambient blood  lymphocyte for healthy people by using Resveratrol, you will see that

72 hours later, comparing with activating ambient lymphocyte individually, no data for Resveratrol to kill the

normal cells.  This proves that Resveratrol has optional power to cancer cells. 


Resveratrol can inhibit protein tyrosine kinase, which is the material to make catalysis of tyrosine. 

Resveratrols inhibition to protein tyrosine kinase is due to act on anti-mutation by inhibiting the function

of kinase.  The mechanism is mainly to inhibit the synthesis of cells of DNA and RNA.

 
 Resveratrol has very strong inhibition to the reaction of lipid peroxidation caused by free radical syste

m, also stronger inhibition to lipid peroxidation on the model of artificial cell of lecithin lipid.  It can obviously

reduce the content of MDA in the tissues, increase the activation of SOD, CAT and GSH-px, thus with

protective effect to cerebral anaemia and tissue damages.


Resveratrol may strengthen the immunity.  It can also recover the inhibited characteristic of cells in the burnt

rat, with effective power to the reactive ability of damagedantigen singal, to breeding ability, to synthetic

ability of white blood cell medium Άς and to synthetic ability of antibody through lymph cell. 

 

STRUCTURAL FORMULA:

                                            

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